Male androgenetic alopecia (AGA) is the utmost frequent kind of male baldness. Objective: This studyaimed to determine serum levels of A-FABP in individuals with AGA and their putative link to the severity of AGA and other metabolic diseases. Methods: This case-control research comprised 60 male patients with AGA and twenty healthy volunteers of the same age and gender. Medical history, clinical examination, and laboratory testing were performed for all individuals. A-FABP serum levels were determined for all subjects. Human A-FABP ELISA kit was used to assess A-FABP in the serum. Participants' A-FABP serum levels were analysed. Results: AFABP levels in AGA patients were substantially higher than in controls. Conclusion: The pathogenesis of AGA may be aided by the presence of serum A-FABP. With its high sensitivity, specificity, and accuracy rate, it might be regarded a biomarker for early illness detection.