Background: One-fifth of the patients suffering from lymphoma had an extra-nodal presentation.
Objectives: We aimed to provide our experience with three cases of cutaneous, lacrimal, and testicular lymphomas.
Patients and methods: We provided three cases with extra-nodal lymphoma arising from the lacrimal gland, the subcutaneous tissue, and testis.
Results: The first case was a 42-year-old lady who presented with relapsed diffuse large B-cell lymphoma (DLBCL) in the form of subcutaneous nodules within both thighs. The second case was 72-year-old lady who presented with an orbital mass. The mass was proven to be NHL arising from the orbit with regional lymphadenopathy. The third case had advanced NHL with testicular and renal involvement. Graphical illustrations of their PET-CT scans were included.
Conclusion: Extra-nodal presentation of NHL is a rare but serious condition. We presented three cases with lacrimal, subcutaneous, and testicular presentation.