Background: Premarital care is a crucial step in preventing unwanted pregnancies, which in turn protects society and allows people to live their lives to the fullest. Objective: Our goal was to find married individuals who have heterozygous familial hypercholesterolemia (HeFH). Subjectives and methods: Six hundred young adults (male and female) with HeFH who were going to get married participated in this cross-sectional research. The following procedures were performed for all patients: comprehensive history taking, clinical data collection, review of family history of coronary artery disease, laboratory testing, and diagnosis of HeFH. Results: The participants that were studied had an average age of 22 ± 3 years. Of the total, 50% were men and 50% were women (50.0 %). Among those who participated in the survey, 55.7% lived in rural areas, while 44.3% lived in metropolitan areas home. At 167 ± 37 mg/dl, the mean total cholesterol was measured. There was an average of 101 ± 37 mg/dl of triglycerides. There was an average of 94.2 ± 31.1 mg/dl for low-density lipoprotein and 52 ± 11 mg/dl for high-density lipoprotein. There was a prevalence of 0.5% of HeFH observed in three cases. Conclusions: Among 600 individuals who were contemplating matrimony, 3 (0.5 %) had potential HeFH.