Background: Choroidal and retinal vascular density (VD) can be evaluated without using any dye with optical coherence tomography angiography (OCTA) through motion contrasting. Objective: This study aimed to assess choroidal changes in solid versus diabetic-retinopathy (DR) patients with/without differed seriousness of DR. Methods: This controlled prospective non-randomized study was carried through the period from April 2021 to April 2022 in Al-Azhar University Hospital, Assiut branch. Results: Raise in Foveal Avascular Zone (FAZ) area in diabetic-retinopathy patients directly proportional to the retinopathy severity and decrease after pan-retinal-photo coagulation. While there is decrease in retinal, choroidal thickness and vessel density in diabetic-retinopathy patients directly proportional to the retinopathy severity and increase after pan retinal photo coagulation. Conclusion:  OCTA identified as pre-clinical DR before the aspect of clinical retinopathy due to the prospect role in monitoring and quantifying retinal and choroidal vascular alterations of diabetes.