Background: Surgery, radiation therapy and chemotherapy are used to treat head and neck cancer (HNC) patients, with the goal of maximizing survival while maintaining physical form and function. Objectives: The study's primary goal was to determine if pulsed high-intensity laser therapy (HILT) was effective in treating cervical myofascial pain and restoring cervical range of motion (ROM) following neck dissection procedures. Subjects and methods: This study  was a randomized controlled trial and  applied to a total number of forty patients from both genders who have cervical Myofascial Pain Syndrome (MPS)  history at upper trapezius muscle (UTM)  at least one month following a unilateral MRND and were randomly assigned into two groups equal in number (20 patients for each group); (HLIT group): received pulsed high intensity laser therapy in addition to traditional physical therapy program and (Control group): received traditional physical therapy program all treatment 3 times per week for one month . Pain was evaluated by Visual analogue scale and pressure algometer, while neck ROM was evaluated by universal goniometer before and after 4 weeks of intervention.  Results: a comparison between the groups showed a significantly lower VAS, significantly higher PPT and a statistically significant difference between the study group's right and left bending and rotation and that of the control group (p < 0.001). Conclusion: Patients with cervical myofascial trigger points were found to benefit greatly from high intensity laser treatment as a kind of physical therapy.