Background: Fungal infections of the nail bed are known as onychomycosis. Nail plate hypertrophy, onycholysis, and nail discolouration are all symptoms. Nail plate, nail matrix, and nail bed are all parts of the nail unit that might be impacted. Objective: Review of literature aboutlines of treatment of onychomycosis. Methods: We searched Science Direct, Google Scholar as well as PubMed for relevant articles on Onychomycosis and Lines of treatment. Only the most recent or thorough study was taken into account between December 2015 and April 2023. The authors also evaluated the value of resources culled from other works in the same genre. Documents written in languages other than English have been ignored due to lack of translation funds. Unpublished works, oral presentations, conference abstracts, and dissertations were generally agreed upon not to qualify as scientific research. Conclusion: Because the fungus lives so deeply within the nail plate, treatment for onychomycosis can take a long time, patients often don't stick with it, and the condition often returns. Possible treatments include surgical avulsion, laser therapy, photodynamic therapy, and both topical and oral antifungal medications (e.g., very thick and chronic fungal nail).