Background: An adaptable group of cells called the immune system in human's works together to defend the body from external threats like malignant cells. The main types of immunity are natural immunity and immunity that is adaptive. The naturally occurring immune system, which is made up of phagocytes white blood cells, dendritic cells (DC), natural killer cells (NK cells), and circulatory plasma proteins, serves as the body's initial line of defence against pathogens. Utilising the cytotoxicity and antigen-specificity of the human immune system, cancer immunotherapy aims to build an effective anti-tumor immune response that can eradicate all cancer cells without causing damage to healthy tissue. Objective: This review article aimed to throw light on updates in cancer immunotherapy. Methods: We searched PubMed, Google Scholar, and Science Direct for relevant articles on Immunity, Cancer immunotherapy and updates. However, only the most recent or thorough study was taken into account between January 2004 and January 2023. The authors also evaluated the value of resources culled from other works in the same genre. Therefore, documents written in languages other than English have been ignored due to a lack of translation funds. Unpublished works, oral presentations, conference abstracts, and dissertations were generally agreed upon not to qualify as scientific research. Conclusion: Immunotherapy, a precise form of cancer treatment, is becoming more popular. Cancer immunotherapy is probably safer than conventional treatments like surgery, chemotherapy, and radiation because it depends on particular genetic makeup of each patient. The majority of cancer patients have either primary or acquired resistance to immunotherapy medications currently on the market, underlining the demand for novel strategies.