Background: Nontunneled hemodialysis catheters and tunneled hemodialysis catheters, often known as tunneled dialysis catheters, are the two catheter types utilised for vascular access during hemodialysis. Short-term (1 week) consequences include catheter malfunction, central vein stenosis or thrombosis, and catheter-related infection. Long-term (>1 week) complications include those occurring during catheter placement and immediate access-related injuries. Objective: Review of literature about complications of central venous catheters of hemodialysis and their prevention in adults. Methods: Central venous catheters and complications were searched for on Science Direct, Google Scholar, and PubMed. The authors also reviewed the relevant literature. Nonetheless, only the most recent or exhaustive analysis was included, covering the time span from January 2005 to December 2022.There are no translation resources available, thus non-English documents are out. Unpublished articles, oral presentations, conference abstracts, and dissertations were not included because they were not considered to be part of major scientific projects. Conclusion: Infection in the bloodstream is a potentially fatal consequence of a central venous catheter (CVC). The best methods for preserving a catheter have been the subject of numerous scientific investigations. This included delaying replacement, exchanging catheters via a wire, or preserving a new catheter with antibiotic locks and systemic antibiotic therapy, but it was clear that removing the contaminated catheter was the best approach to get rid of the organism.