Background: In addition to atherosclerosis, non-atherosclerotic occlusive disease and vasospasms all contribute to coronary artery disease (CAD). The leading cause of CAD, atherosclerosis, continues to be a leading contributor to mortality as well as disability globally. Several possible indicators and imaging techniques exist with the potential to enhance diagnosis accuracy in stable CAD. Stress echocardiography and computed tomography coronary angiogram are two of the most prominent imaging techniques. Objective: Review of literature about Stress echocardiography and Risk stratification in patients with suspected ischemic heart disease. Methods: Ischemic heart disease and Stress Echocardiography were searched for on Science Direct, Google Scholar, and PubMed. The authors also reviewed the relevant literature, Nonetheless, only the most recent or exhaustive analysis was included, covering the time span from January 1997 to August 2021.There are no translation resources available, thus non-English documents are out. Unpublished articles, oral presentations, conference abstracts, and dissertations were not included because they were not considered to be part of major scientific projects. Conclusion: The use of stress echocardiography has expanded greatly in recent years as a diagnostic and prognostic tool for patients suspected of having coronary artery disease (CAD).