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296191

An Overview of Thymectomy Approaches among Myasthenia Graves Patients: Review Article

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Last updated: 03 Jan 2025

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Abstract

Background: Myasthenia gravis (MG) is a syndrome characterized by fatigue- and activity-induced improvements in skeletal muscular weakening. There is a wide range of possible involvement, including but not limited to the muscles of the eyes, face, oropharynx, trunk, and limbs. Once the patient's level of weakness has been managed to the point that surgery is possible, thymectomy is recommended. Preoperatively, patients are typically treated with mild doses of intravenous immunoglobulins as well as glucocorticoids. Objective: Review of the literature on thymectomy approaches among myasthenia graves' patients. Methods: We scoured medical journals and databases including PubMed, Google Scholar, and Science Direct for information on thymectomy and myasthenia graves. Between September 2006 and August 2022, however, only the latest or most comprehensive study was considered. The authors also assessed the usefulness of references drawn from similar books. Documents written in languages other than English have been overlooked because of lack of funding to translate them. Unpublished articles, oral talks, conference abstracts, and dissertations were all generally agreed upon not to constitute valid scientific investigation. Conclusion: It has been argued that a maximum thymectomy, in which both the transsternal and transcervical techniques are used on the same MG patient, yields superior results. After extensive transsternal thymectomy or video-assisted thoracoscopic thymectomy, half of patients with non-thymomatous MG had complete stable remissions at 6 years of follow-up.  

DOI

10.21608/ejhm.2023.296191

Keywords

thymectomy, Myasthenia graves

Authors

First Name

Mahmoud Ahmed Abdelsamed

Last Name

Desoky

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Affiliation

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Email

mahmoudsab3awy931994@gmail.com

City

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Orcid

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First Name

Elrady Kamal

Last Name

Emam

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Ehab Sobhy

Last Name

Ragab

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Ahmed Mahmoud Ahmed

Last Name

Shafeek

MiddleName

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Affiliation

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Email

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City

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Orcid

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Volume

91

Article Issue

1

Related Issue

40609

Issue Date

2023-04-01

Receive Date

2023-04-23

Publish Date

2023-04-01

Page Start

4,230

Page End

4,235

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_296191.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=296191

Order

68

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

An Overview of Thymectomy Approaches among Myasthenia Graves Patients: Review Article

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Article

Created At

24 Dec 2024