Background: Tissue Doppler Imaging (TDI) modality is frequently utilized to evaluate cardiac function. TDI velocities and timings vary with age and growth. Data about normal TDI values in the first two years of life is limited. Also, reference values of TDI differ according to racial and environmental factors. Objective: This research aimed to identify the normal values and introduce Z scores for left ventricular pulsed TDI timings and velocities in Egyptian children as well as investigate the impact of age, heart rate (HR), body surface area (BSA), and gender on TDI timings and velocities. Methods: For 208 healthy children with an age range between two months and two years, a pulsed TDI examination was applied using the apical four chamber view at the septal and lateral mitral annuli during ventricular systole and early and late diastole. We measured systolic, early and late diastolic velocities, isovolumic contraction, isovolumic relaxation and ejection times (ETs).  Also, mitral closure to opening time (MCOT) and Tie index were obtained. The association between TDI velocities and timings and different demographic variables were analyzed using linear regression model. Results: Normal values and Z score graphs for most of left ventricular TDI velocities and time intervals were demonstrated. TDI velocities and timings were positively correlated with age and BSA while negatively correlated with HR and not affected by sex. Conclusion: We present reference values of left ventricular TDI parameters in pediatric Egyptian children from two months to two years of age and demonstrate the effect of growth on TDI velocities.