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292762

Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men

Article

Last updated: 03 Jan 2025

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Abstract

Background: Primary premature ejaculation (PE) can be effectively treated with sildenafil citrate, according to recent research. This study evaluated sildenafil citrate efficacy in primary PE treatment, considering the female perspective. Methods: Sixty sexually active men diagnosed with primary PE were split into two groups randomly and followed for 6 months. Group A received 50 mg of sildenafil citrate one hour before sexual activity in accordance with standard dosing guidelines (not fewer than once a week), while Group B received paroxetine 20 mg daily for six months. At baseline, 3 months, and 6 months following therapy, the intravaginal ejaculatory latency time (IELT), PE grade, intercourse satisfying score (ISS), intercourse frequency, and drug-associated side effects were noted. Results: Both groups showed significant improvements in all measurements following 3 or 6 months of therapy, with no critical changes between two time points. However, sildenafil citrate was found to be significantly more effective than paroxetine in improving all parameters at both 3 and 6 months (P = 0.001). Conclusion: Sildenafil citrate is a highly beneficial treatment for primary PE and is more effective than paroxetine.  

DOI

10.21608/ejhm.2023.292762

Keywords

Premature Ejaculation, Sildenafil citrate, Paroxitine

Authors

First Name

Ahmed

Last Name

Abdel Fattah

MiddleName

Abou Elezz

Affiliation

Department of urology,faculty of medicine.Benha University, Benha,Egypt

Email

ahmed.aboelezz@fmed.bu.edu.eg

City

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Orcid

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First Name

Basheer Nagy

Last Name

Elmohamady

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Salah A.

Last Name

El Hamshary

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Hosam

Last Name

Abu El-Nasr

MiddleName

-

Affiliation

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Email

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City

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Orcid

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Volume

90

Article Issue

2

Related Issue

39562

Issue Date

2023-01-01

Receive Date

2023-03-29

Publish Date

2023-01-01

Page Start

3,620

Page End

3,624

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_292762.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=292762

Order

319

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Efficacy of Sildenafil Citrate in Treatment of Primary Premature Ejaculation in Men

Details

Type

Article

Created At

24 Dec 2024