Background: There is a large deal of heterogeneity in the clinical appearance, duration, and course of the disease among children who wheeze and have recurrent coughs. Objectives: To evaluate clinically, epidemiologically and laboratory the children attended to Al-Azhar Assuit University Hospital by coughing and wheezing. Subjects and methods: This study is a retrospective study between 1^st March 2020 and the 28^th February 2021 and prospective study between 1^st March 2021 and 30^th November 2021 and was carried out in outpatient and inpatient Pediatric Chest Unit in Al-Azhar Assuit University Hospital. Result: Among the studied cases (Total n=324), there were 106 (32.8%) suffered from bronchial asthma, 81 (25%) suffered from pneumonia, 63 (19.4%) suffered from bronchiolitis, 27 (8.3%) suffered from COVID-19 and 47 (14.5%) suffered from other cases such as bronchitis, GERD, lung abscess and F.B. Conclusion: Cough in pediatric is due to multiple underlying causes, the most common are bronchial asthma, pneumonia, bronchiolitis, COVID-19, foreign body aspiration, and gastroesophageal reflux. Bronchial asthma was more prevalent among age (6-12) years but pneumonia was among age (1-6) years, bronchiolitis was among age (1-2) years and COVID-19 was among age (12-18) years. Bronchial asthma and infections as pneumonia and bronchiolitis had declined among breast feeding cases.