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290996

Role of Speckle Tracking Echocardiography in Assessing Anginal Chest Pain on Exertion

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Last updated: 03 Jan 2025

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Abstract

Background: Left bundle branch block (LBBB) poses some restriction on coronary artery disease (CAD) diagnosis with noninvasive diagnostic modalities. Objectives: Evaluating the role of 2-D speckle tracking echocardiography (STE) in the diagnosis of CAD in patients with LBBB. Patients and Methods: This was asingle-center observational prospective study that lasted for 3 years. 80 patients with LBBB complaining of exertional chest pain underwent STE and coronary angiography (CA). Results: 50 patients were put in group I, on exclusion of significant CAD. Group II had 30 patients having significant CAD on CA. Global longitudinal strain (GLS) of the left ventricle was higher in group II patients (p value of 0.0001). Also, time to peak strain in apical 2 chamber view (TTPS AP2), apical 3 chamber view (TTPS AP3) and apical 4 chamber view (TTPS AP4) were significantly higher among group II patients (p-value of 0.0001, 0.0001 and 0.0001 respectively). GLS can predict significant CAD using cutoff point of 11.4%, with sensitivity of 66% and specificity of 90% (p-value 0.0001). TTPS AP2 can predict significant CAD using cutoff point of 399.5 milliseconds (ms), with a sensitivity of 90% and specificity of 58% (p value 0.0001). TTPS AP3 can predict significant CAD using cutoff point of 385.5 ms, with a sensitivity of 73.3% and specificity of 72% (p-value of 0.0001). TTPS AP4 can predict significant CAD using cutoff point of 377.5 ms, with sensitivity of 90% and specificity of 52% (p-value of 0.0001). Conclusion: STE could be valuable in the assessment of LBBB patient with suspected CAD.  

DOI

10.21608/ejhm.2023.290996

Keywords

Global longitudinal strain (GLS), Left bundle branch block (LBBB), speckle tracking echocardiography (STE), Time to peak strain (TTPS), Coronary artery disease (CAD), Coronary angiography (CA)

Authors

First Name

Ahmed Y.

Last Name

Nammour

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Orcid

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First Name

Marwa

Last Name

Hassanein

MiddleName

Wahba

Affiliation

cardiology department, students hospital, Cairo university

Email

wahbamarwa@gmail.com

City

Banha

Orcid

-

First Name

Metwally H

Last Name

Elemry

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Mohammed M.

Last Name

Ali

MiddleName

-

Affiliation

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Email

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Volume

90

Article Issue

2

Related Issue

39562

Issue Date

2023-01-01

Receive Date

2023-03-16

Publish Date

2023-01-01

Page Start

3,195

Page End

3,199

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_290996.html

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https://ejhm.journals.ekb.eg/service?article_code=290996

Order

184

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Role of Speckle Tracking Echocardiography in Assessing Anginal Chest Pain on Exertion

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Article

Created At

24 Dec 2024