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290606

New Treatment Strategies in Management of Alopecia Areata: Review Article

Article

Last updated: 03 Jan 2025

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Abstract

Background: Alopecia areata is a common and unpleasant illness that manifests as abrupt, circular patches of complete hair loss that heal scar-free. For most individuals with patchy alopecia areata, intralesional or topical corticosteroids are regarded the first therapeutic option due to their relative safety and convenience; nevertheless, there is limited evidence for their efficacy. Objective: Review of the literature on New Treatment Strategies in Management of Alopecia Areata. Methods: We looked for data on New Treatment Strategies and Alopecia Areata, treatment in medical journals and databases like PubMed, Google Scholar, and Science Direct. However, only the most recent or extensive study was taken into account between November 2002 and December 2021. References from related works were also evaluated by the writers. There are not enough resources to translate documents into languages other than English, hence those documents have been ignored. It was generally agreed that documents such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations did not qualify as legitimate scientific study. Conclusion: When a ligand attaches to their specific cytokine receptor, janus kinases (JAKs) can phosphorylate signal transducers and activators of transcription (STATs). Hair regrowth is facilitated by oral formulations because they are simple to ingest. Tofacitinib comes in 5-mg and 11-mg doses and can be taken once or twice day. Treatment options for alopecia areata of the scalp are limited, but the 308-nm excimer laser has proven to be helpful in restoring hair growth in affected areas.  

DOI

10.21608/ejhm.2023.290606

Keywords

New Treatment, Alopecia Areata, Scar-free, hair loss

Authors

First Name

Mohamed Metwalli

Last Name

Abdelnabi

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First Name

Mohamed Mahmoud

Last Name

Nasr

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Ahd Ismail Mousa

Last Name

Mohamed

MiddleName

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Affiliation

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Email

ahdismail21@gmail.com

City

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Orcid

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First Name

Lamiaa Mahmoud

Last Name

Kamel

MiddleName

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Affiliation

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Volume

90

Article Issue

2

Related Issue

39562

Issue Date

2023-01-01

Receive Date

2023-03-14

Publish Date

2023-01-01

Page Start

3,133

Page End

3,137

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_290606.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=290606

Order

173

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

New Treatment Strategies in Management of Alopecia Areata: Review Article

Details

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Article

Created At

24 Dec 2024