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288373

Ultrasonographic Measurement of Distal Femoral and Proximal Tibial Epiphyseal Ossification Centers in the Third Trimester and their Correlation to Gestational Age

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Last updated: 03 Jan 2025

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Abstract

Background: Sonographic estimations are derived from calculations based on fetal measurements and thus, serves as an indirect indicator of maturity and GA.  Objective: This study aimed to measure the distal femoral (DFOC) and proximal Tibia (PTOS) epiphyseal ossification centers in the 3rd trimester and correlate them to BPD, HC, AC, FL and GA to increase the ultrasound accuracy of gestational age (GA) estimation and thus avoiding iatrogenic prematurity. MethodS: A prospective observational cohort study. A total of 150 low risk pregnant women. The Distal Femoral and the Proximal Tibia epiphyseal ossification centers were measured and correlate them to BPD, HC, AC, FL and GA. Results: The best cut-off of DFOC in prediction of maturity (GA ≥ 37th weeks' gestation) was  ≥ 4.4 mm with area under curve 0.88 (CI: 0.83 to 0.94) with sensitivity 82.8%, specificity 79.3%, positive predictive value (PPV) 95%, negative predictive value (NPV) 49% and overall accuracy 80% (p < 0.001), the best cut-off of PTOC in prediction of maturity (GA ≥ 37th weeks' gestation) was ≥ 2.5 mm with area under curve 0.887 (CI: 0.83 to 0.95) with sensitivity 82.8%, specificity 74.4%, positive predictive value (PPV) 95%, negative predictive value (NPV) 44% and overall accuracy 76% (p < 0.001). Conclusion:  There was a strong positive correlation between DFOC, PTOC and GA.  

DOI

10.21608/ejhm.2023.288373

Keywords

Ultrasound, Gestational age, Distal femoral, Proximal tibia, Ossification centers

Authors

First Name

Nadia M.

Last Name

Madkour

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Orcid

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First Name

Badeea S.

Last Name

Soliman

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Orcid

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First Name

Dalia Zakareya

Last Name

Hussein

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Email

daliazakareya9@gmail.com

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First Name

Ahmed Hassan

Last Name

El-Massarawy

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Volume

90

Article Issue

2

Related Issue

39562

Issue Date

2023-01-01

Receive Date

2023-03-03

Publish Date

2023-01-01

Page Start

3,009

Page End

3,014

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_288373.html

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https://ejhm.journals.ekb.eg/service?article_code=288373

Order

154

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Ultrasonographic Measurement of Distal Femoral and Proximal Tibial Epiphyseal Ossification Centers in the Third Trimester and their Correlation to Gestational Age

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Article

Created At

24 Dec 2024