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287339

Myopathic Changes in Patients with Long-term Fatigue after COVID-19

Article

Last updated: 03 Jan 2025

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Abstract

Background: Neurological symptoms during the acute infection include headache, disorientation, critical disease myopathy, stroke, abnormal cerebral perfusion, and leptomeningeal augmentation, as well as Guillain-Barre syndrome. Objective: The aim of the current study was to look at the electrical activity of peripheral nerve and muscle in patients who had COVID-19-related continuing neuromuscular symptoms. Patients and methods: This study was conducted in the period from Jan 2022 to June 2022. A total of 50 patients participated in the study. All patients were monitored at the Neurology Department of Alazhar University Hospital, New Damitta. In addition, 50 healthy controls matched for age and sex were recruited. All patients and healthy controls completed a thorough clinical assessment and neurological examination, which included force measurement, deep tendon reflex testing, and sensory evaluation, on the day of the neurophysiological assessment. The three average neuropathy ratings for each patient were also recorded; The Utah Early Neuropathy Score (UENS), the Michigan Neuropathy Screening Instrument (MNSI), and the Neuropathy Impairment Score (NIS). Results: No statistical significant difference was found between the 2 studied groups regarding sex, age or BMI.The results of the studied groups' quantitative electromyography (qEMG), nerve conduction studies (NCS), Peroneal MCV (m/sec), Tibial MCV (m/sec), and Tibial minimum F-wave delay revealed extremely substantial difference between case and control groups. Sural SCV (m/sec), or Sural SNAP amplitude (mV), with the exception of Ulnar MCV (m/sec), Ulnar Palpitations, physical weariness, and myalgia all were significantly higher in the case group. Conclusion: A typical finding in long-term COVID-19 is myopathic qEMG. We suggest that myopathy may play a significant role in these individuals' physical exhaustion.  

DOI

10.21608/ejhm.2023.287339

Keywords

Myopathic changes, long-term, Fatigue, COVID-19, Case control study, Alazhar University Hospital

Authors

First Name

Elsayed Fathi Ali

Last Name

Hamed

MiddleName

-

Affiliation

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Email

drsayedfathy@gmil.com

City

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Orcid

-

Volume

90

Article Issue

2

Related Issue

39562

Issue Date

2023-01-01

Receive Date

2023-02-25

Publish Date

2023-01-01

Page Start

2,847

Page End

2,851

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_287339.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=287339

Order

128

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Myopathic Changes in Patients with Long-term Fatigue after COVID-19

Details

Type

Article

Created At

24 Dec 2024