Background: For its lasing medium, a dye laser uses a solution of organic dye in a solvent. Among the laser dyes are rhodamine, fluorescein, coumarin as well as malachite green. In addition to water and glycol, other solvents include ethanol, methanol, hexane, cyclohexane, and cyclodextrin. The time it takes for the target structure to drop to half its peak temperature after being irradiated by a laser is shorter than the pulse duration of the laser energy. Objective: Review of the literature on Dermatological Uses of Pulsed Dye Laser. Methods: We looked for data on laser therapy and pulsed dye laser, treatment in medical journals and databases like PubMed, Google Scholar, and Science Direct. However, only the most recent or extensive study was taken into account between December 2001  and February 2022. References from related works were also evaluated by the writers. There are not enough resources to translate documents into languages other than English, hence those documents have been ignored. It was generally agreed that documents such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations did not qualify as legitimate scientific study. Conclusion: Pulsed dye laser (PDL) therapy has shown promise in the treatment of a variety of skin conditions. Port wine stains can be removed using PDL (vascular malformation), cherry angiomas, telangiectasias, and poikiloderma of Civatte are examples of acquired cutaneous vascular lesions.