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285688

Antibacterial and Antibiofilm Activity of Calcite (CaCO3) Nanoparticles Synthesized from Chicken Eggshell

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Last updated: 24 Dec 2024

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Abstract

 Background: The Calcite Calicium Carbonate Nanoparticles (CaCO3NPs) synthesized from the chicken eggshell (CES), this was done by crushing the shell and sieving. Objective: The aim of the current study is to find a way to benefit from CES residues and the possibility of exploiting them in the production of CaCO3NPs, which is used in many medical applications. Material and methods: A hundred burn wounds samples were collected from several clinical sources. A total of 60 bacterial isolates were obtained from the burn wounds. CaCO3NPs has effective antibacterial activity; the inhibition zone was 12 mm for Acinetobacter baumannii, Proteus mirabilis and Staphylococcus aureus, 13 mm for Escherichia coli, 11 mm for Klebsiella pneumoniae, 14 mm for Burkholderia cepacia, and Pseudomonas aeruginosa. Results: The results showed that the MIC for A. baumannii was 25 µg/ml. The same MIC values were for K. pneumoniae and S. aureus, while B. cepacia, E. coli, P. mirabilis, and P. aeruginosa have the MIC was 6.25 µg/ml. The present study shows the efficiency of CaCO3NPs to prevent the biofilms of Gram negative and Gram-positive isolates. Conclusion: Synthesized CaCO3NPs from the chicken eggshell have biological effectiveness and it can be used in dental fillings and bone repair.  

DOI

10.21608/ejhm.2023.285688

Keywords

Burn wound, Pathogenic bacteria, Chicken eggshells, CaCO3NPs, Antibacterial activity, antibiofilm activity, University of Baghdad

Authors

First Name

Mundher H.

Last Name

Al-Azzawi

MiddleName

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Affiliation

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Email

monzer.hussein1202a@ihcoedu.uobaghdad.edu.iq

City

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Orcid

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First Name

Esam J.

Last Name

Al-Kalifawi

MiddleName

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City

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Orcid

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Volume

90

Article Issue

2

Related Issue

39562

Issue Date

2023-01-01

Receive Date

2023-02-15

Publish Date

2023-01-01

Page Start

2,275

Page End

2,282

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 90_Issue 2_Pages 2275-2282.pdf

PDF . 948.2kB

Link

https://ejhm.journals.ekb.eg/article_285688.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=285688

Order

43

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Antibacterial and Antibiofilm Activity of Calcite (CaCO3) Nanoparticles Synthesized from Chicken Eggshell

Details

Type

Article

Created At

24 Dec 2024