Background: Despite the fact that warts, the microscopic skin protuberances caused by the human papillomavirus, do not pose any serious health risks, they can be unattractive, unpleasant, uncomfortable, and even contagious. It's possible they'll regress on their own, but it could take a long time. As a result, many who have them look for treatments both professionally and commercially. As of yet, there is no one-and-done solution for curing warts with minimal adverse effects. Pain, burning, blisters, local irritation, bleeding, infection, ulcers, and scarring are only some of the potential side effects of destructive therapy. Objective: Review of the literature on therapy lines for treatment of warts. Methods: We looked for data on therapy and warts treatment in medical journals and databases like PubMed, Google Scholar, and Science Direct. However, only the most recent or extensive study was taken into account between January 2000 and May 2021. References from related works were also evaluated by the writers. There are not enough resources to translate documents into languages other than English, hence those documents have been ignored. It was generally agreed that documents such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations did not qualify as legitimate scientific study. Conclusion: Warts can be treated in a number of ways, the most common being chemical cautery laser ablation, cryotherapy, surgical excision, electrocautery, surgical excision,   immunotherapy, which involves stimulating the immune system to attack the virus and suppress its activity.