Background: Using platelet rich plasma (PRP) was associated with more improvement in activity limitation and physical disability when compared with corticosteroids and even with surgical management. Objective: The aim of the study is to evaluate the effect of local PRP injection on chronic plantar fasciitis resisting the conservative modalities of treatment. Patients and Methods: This is a prospective interventional study of 30 patients for 6 months. 18 males and 12 females with planter fasciitis were included in this study. Their ages ranged from 35 to 62 years with a mean age of 44.5 years. Patients with widespread inflammatory arthritis, any wound or skin lesion on the plantar aspect of the foot, previous surgery for heel pain, and other local pathologies for heel pain were excluded. Their improvement was measured by Ankle Hindfoot Scale. Results: The Ankle Hindfoot Scale showed a statistically significant (p-value 0.02) improvement over time. Acceptable results were obtained in 70% (n=21) of patients from a single injection and 30% (n=9) needed a second injection. Chronic plantar fasciitis that is resistant to conventional treatment techniques can be effectively treated with local PRP injection. Conclusion: For severe plantar fasciitis that is resistant to conservative treatment approaches, local PRP injection is an effective therapy.