Background: Technology is used in every aspect of life. On the level of professional life, it has great benefits in increasing productivity. Unexpectedly, it could negatively impact productivity through technology-induced stress (Technostress). Objectives: This study aimed to study the effect of technostress and work stress on productivity. In addition to studying other associated factors of productivity. Patients and methods: This was a cross-sectional study conducted on 337 staff members of the Faculty of Medicine of Zagazig University from July to September 2022. A survey was used to collect the questionnaire. Results: Age, years spent on the job, degree, and training were significantly associated with productivity. Three out of five techno-stressors (techno-complexity, techno-insecurity,techno-uncertainty) in addition to role conflict were associated with productivity. Techno-uncertainty is the only significant predictor of productivity. Conclusions: Technostress is a new but important phenomenon that could affect productivity so we should pay attention to it. In addition to that, some other factors associated with productivity such as training and role conflict are believed to be modifiable factors.