There is a rare of information regarding the influence of age on cerebrospinal fluid (CSF) and blood components of the one-humped camels. To demonstrate these relationships, CSF and blood were collect d from two age groups of male camels (l- >3 and 3-5 years). Most of CSF tested parameters urea, creatinine, uric acid, total protein, non albumin protein) in large age group were showed a significant difference relative to small age camel group except for glucose, albumin and electrolytes contents (Na, Kand Cl). Age had no significant effect on the serum component except for urea, creatinine and uric acid in the both age groups. These differences especially in CSF pa­rameters between the two age groups may suggest that blood-brain barrier is not at the same stage of maturation or selective permeability.