Goats play an important role in the epidemiology and transmission of Food and Mouth Disease (FMD). It is important to identify animals which were exposed to the virus and have developed antibodies. Such animals may become carriers and thus be a potential source of a new outbreak. Certain viral non-structural proteins (NSN) are produced during the process of infection by FMD virus (FMDV) and against which immunoglobulin may be formed; the most reliable single NSP indicator is the poly-protein 3ABC, antibodies which appear to provide conclusive evidence of previous infection, whether the animals have been vaccinated or not. A Serosurvey was done in different provinces in Egypt to detect the infected goats by FMDV through using different serological test. Serum Neutralization test, ELISA and FMDV-3ABC ELISA. It was found that goats gave a positive result to FMDV-3ABC ELISA which indicates the presence of previous infection between goats which reminded sub clinical and acted as a carrier and as a source of infection causing outbreaks between other species as cattle, sheep and buffaloes.