The study was carried out on 106 non-gravid uteri of slaughtered ewes in Cairo slaughter house. Blood and tissue samples were collected and used for serological, bacteriological and histopathological examination. Endometritis was detected in 48.1% of examined cases, which were divided into: non suppurative endometritis (33 cases), acute suppurative endometritis (6 cases), chronic suppurative endometritis (7 cases) and granulomatous endometritis (cases). Two cases of granulomatous endometritis showed spherical yeast- like fungi invading the epithelial covering. Toxoplasma gondii and Salmonella spp. Antibodies were detected in 31(29.2%) and 21 (19.8%) cases of endometritis respectively .