The disease of pigs have received little attention in Egypt. There have been few published papers of virus isolation or surveys for virus antibodies as (Abo El- Hassan et al., 1989) who detected antibodies to RP virus in pig's sera and (Youssef et al., 1990) who demonstrated FHDV antibodies in swine sera. Rinderpest is an endemic disease in Egypt, which flaired up among cattle and buffaloes at many farms in Egypt during Narch 1982 causing severe outbreaks and resulted in great economic losses (Abo El-Hassan 1986). The sudden onset of this outbreak in spite of mass vaccination draw the attention to search for animals which may act as reservoir or inapparently contract the disease and disseminate the virus. Natural infection of pigs with BVDV through contact with infected cattle has been reported by (Flynn and Jobes 1964). SVD infection in pigs causes false positive reaction to test for swine fever (SF) or Hog Cholera (HC) anti- bodies and may protect against subsequent challenge with HCV. The importance of this and other species as source of infection for cattle is unknown but it is likely that they can act as carrier host. BRV affects swine naturally in both the respiratory and genital form (Nelson et al. 1972). The virus was isolated from a boar affected with balanitis, from sows affected with vaginitis and from the vagina of a healthy sow (Saxegard and Anstad 1967). Cattle are believed to be the principal reservoir of IBRV but the role played by swine and other species as reservoir is still unknown. The aim of this investigation is to screen the antibodies to PRV, BVDV and IBRV in swine sera in order to clarify their role in establishing such infection.