Respiratory distress was shown to be problem in 1200 friesian calves belonging to military farm,El-Tall El-Kabeer. Ismailia Governorate, Egypt. The problem began two weeks after importation and transportation of calves from western Nobaria
to El-Tall El-Kabeer farm. The clinical signs observed were fever, dyspnea, nasal and ocular discharge, Conjunctivitis, corneal opacity and occasionally coughing. Some complicated cases were emergency slaughtered or died. The signs were more serious in young calves (6-10 months) than in older calves (11-15 months). The morbidity rate was 77.16% while, the mortality rate was 6.59%. Nasal and ocular swabs were taken for virological and bacteriological examinations. Also paired serum samples were collected from diseased calves for serum neutralization test (SNT). Bovine herpesvirus type 1 (BHV-1) was isolated on MDBK cell line and confirmed by virus _ by the strain of virus, dose and route of exposure
neutralization test (VNT). SNT revealed high titer which reached up to 1/320. In complicated cases Pasteurella haemolytica. Trasportation, overcrowding, and bad weather  were considered to be predisponing factors for the 
disease. Injection of Enrofloxcin 10% (cidotryl-cid, Egypt, 1ml/40Kg. B. W.) and tonics were given to mininize the course of the disease and secondary bacterial complication.