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376612

EFFECT OF XYLAZINE ON SOME ENDOCRINOLOGICAL AND HAEMATOLOGICAL PARAMETERS IN HEIFERS UNDER THERMONEUTRAL OR HEAT STRESS CONDITIONS

Article

Last updated: 23 Dec 2024

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Subjects

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Tags

Physiology/endocrinology

Abstract

A study was performed to assess the effect of xylazine HCI (0.1 mg/kg of body weight, IV) in heifers maintained at thermoneutral (TN; 18°C, 42% RH) or heat stress (HS;33°C, 63% RH) conditions. Xylazine injection resulted in a sharp increase (P<0.05) in serum cortisol levels after 15 minutes in both groups. However, cortisol levels gradually declined and reached basal levels after 45 minutes and 3 hours in heifers maintained under TN and HS conditions, respectively. Xylazine administration increased (P<0.05) serum T3 concentrations after 15 and 30 minutes in the thermoneutral and heat-stressed animals, respectively. Serum T3, however, gradually decreased and reached basal values after 3 hours in both groups. The xylazine-treated heifers had lower (P<0.05) red blood cells, haemoglobin and packed cell volume under TN conditions, while higher (P<0,05) values were observed under HS conditions. All the above parameters were greater (P< 0.05) in the thermoneutral animals than in the heat-stressed ones either before or after xylazine administration. It is possible that an undesirable interaction occurred between xylazine and the hot environment, thus it is suggested that xylazine should be used cautiously in hyperthermic animals.

DOI

10.21608/vmjg.2024.376612

Authors

First Name

ABDALLA

Last Name

B.

MiddleName

-

Affiliation

Fac. of Agric., Ain Shams Univ., Shobra El-Kheima, Egypt.

Email

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City

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Orcid

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First Name

FAYED

Last Name

H.

MiddleName

-

Affiliation

Fac. of Vet. Med., Alex. Univ., Edfina, Egypt.

Email

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City

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Orcid

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Volume

44

Article Issue

2

Related Issue

50020

Issue Date

1996-04-01

Receive Date

2024-08-27

Publish Date

2024-08-27

Page Start

507

Page End

513

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 44_Issue 2_Pages 507-513.pdf

PDF . 4.9MB

Link

https://vmjg.journals.ekb.eg/article_376612.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=376612

Order

376,612

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

EFFECT OF XYLAZINE ON SOME ENDOCRINOLOGICAL AND HAEMATOLOGICAL PARAMETERS IN HEIFERS UNDER THERMONEUTRAL OR HEAT STRESS CONDITIONS

Details

Type

Article

Created At

23 Dec 2024