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377262

CYTOTOXIC EFFECTS OF THE PYRETHROID INSECTICIDE (MATOX)® WITH REFERENCE TO ITS INFLUENCE ON THE REPRODUCTIVE HORMONE

Article

Last updated: 23 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Pharmacology
Physiology/endocrinology

Abstract

Male rats exposed 10 the aerosols of the | pyrethroid insecticide (Matox)™ at a level of one Flet/36 m3 for 10 hours daily up 10 2,4 and 8 weeks revealed a significant decrease in weight of testis epididymis. seminal vesicle and prostate glands after 4 and 8 weeks. The sperm motility percentage was significantly decreased after 2,4 and 8 weeks of exposure to Matox aerosols while the sperm cell concentration was significantly decreased after 4 and 8 weeks of exposure to Matox aerosols. Male rats exposed to Matox aerosols showed a significant decrease in the level of LH and  testosterone hormone after 4 and 8 weeks. Meanwhile, the FSH level was reduced only after 8 weeks of exposure.  Cytogenetic studies revealed that Matox have either visible effect on chromosomes structure  and arrangement nor numerical chromosomal aberrations. However, the miotic division of testicular cells in Matox treated group were highly significantly decreased when compared with  of control one. Hematological studies showed that Matox aerosols induced a significant decrease in R.B.Cs.  and W.B.C counts, Hb content and PCV after 2,4 and 8 weeks.

DOI

10.21608/vmjg.1993.377262

Authors

First Name

ASHMAWY

Last Name

ZAKARIA

MiddleName

-

Affiliation

Pharmacology Dept, Fac. Vet. Med., Alex Univ, Egypt

Email

-

City

-

Orcid

-

First Name

ALD

Last Name

HEMED

MiddleName

-

Affiliation

Physiology Dept, Fac. Vet. Med., Alex Univ, Egypt

Email

-

City

-

Orcid

-

First Name

SHA EL-FIKEY

Last Name

S

MiddleName

-

Affiliation

Genetics Dept, Fac. Vet. Med., Alex Univ, Egypt

Email

-

City

-

Orcid

-

First Name

HUSSEIN

Last Name

Y

MiddleName

-

Affiliation

Forensie Fac. Vet. Med., Alex Univ, Egypt

Email

-

City

-

Orcid

-

Volume

41

Article Issue

3

Related Issue

49974

Issue Date

1993-07-01

Receive Date

2024-08-30

Publish Date

1993-07-01

Page Start

125

Page End

130

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 41_Issue 3_Pages 125-130.pdf

PDF . 2.7MB

Link

https://vmjg.journals.ekb.eg/article_377262.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=377262

Order

377,262

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

CYTOTOXIC EFFECTS OF THE PYRETHROID INSECTICIDE (MATOX)® WITH REFERENCE TO ITS INFLUENCE ON THE REPRODUCTIVE HORMONE

Details

Type

Article

Created At

23 Dec 2024