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371892

BIOCHEMICAL DISORDERS IN SERUM OF TILAPIA NILOTICA EXPOSED TO DIAZINON FOR MEDIUM TERM

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Biochemistry
Physiology/endocrinology

Abstract

Diazinon is an organophosphorus pesticide that Commonly used in eradication of insects. Fish is One of the non-target organisms that may be exposed to diazinon toxicity. In this investigation We studied the effect of exposure of Tilapia nilotica to diazinon at concentrations of 40, 80 and 160 PPM for one, two and four weeks. Lipids profile, Proteins content, proteins fingerprint, bilirubin, Thyroid hormones and certain enzymes activity (GST, CK and AchE) of treated fish serum were Determined. The same parameters were followed Also after a period of ten days of recovery. Dramatic changes were found in most of the measured parameters at all tested concentrations and Times of exposure. Serum protein fractionation by SDS-PAGE revealed disappearance of certain Protein fractions at the different concentrations of Diazinon. Some of these fractions were reappeared again after the recovery period indicating The depressing effect of diazinon on the expression of certain genes.

DOI

10.21608/vmjg.2001.371892

Keywords

Diazinon Tilapia nilotica, SDS- PAGE, Medium term, biochemistry

Authors

First Name

M

Last Name

GHONEIM

MiddleName

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Affiliation

Depts. Of Biochemistry, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt

Email

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City

-

Orcid

-

First Name

E

Last Name

EL-KHATIB

MiddleName

-

Affiliation

Dept. Mammalian Toxicology, Central Agricultural, Pesticides Laboratory, Egypt.

Email

-

City

-

Orcid

-

First Name

M

Last Name

ATTIA

MiddleName

-

Affiliation

Depts. Of Physiology, Faculty of Veterinary Medicine, Cairo University, Giza 12211

Email

-

City

-

Orcid

-

Volume

49

Article Issue

1

Related Issue

49660

Issue Date

2001-01-01

Receive Date

2024-08-05

Publish Date

2001-01-01

Page Start

131

Page End

146

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 49_Issue 1_Pages 131-146.pdf

PDF . 5.4MB

Link

https://vmjg.journals.ekb.eg/article_371892.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=371892

Order

371,892

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

BIOCHEMICAL DISORDERS IN SERUM OF TILAPIA NILOTICA EXPOSED TO DIAZINON FOR MEDIUM TERM

Details

Type

Article

Created At

23 Dec 2024