The effect of sewage water pollution on growth performance, survival rate and food conversion of O. niloticus (8.0 cm for total length and 12.0 gm for body weight) was studied for 91 days. The fish were stocked at a density of one fish /5 liters in glass aquaria (150 liters each). It was Observed that the maximum values of final weight, specific growth rate and normalized (15.4 ‘gm, 3.2 and 6.14 'espectively) were observed in aquarium 2 (75 biomass index % freshwater and 25 % pollutant water).The survival rate of rearing fish was gradually decreased with the increasing of sewage water Pollution, while the food conversion and Ondition factor increased. It was also noticed Ihal the fish Production reached its highest value (0.95 ky) in the second pollutant Ievel.