172 cattle ( 124 freisian and 48 native breed ) in Sharkia and Ismailia governorates, Egypt, suffer- were noticed in the epidermis of the examined warts. Virological and histopathological results revealed infection with bovine papilloma virus and suggested type II. “4 ing from skin cruptions represented by wart – like lesions on head, neck, dewlap, eye lids and occa- Spontancous recovery had occurred in mild cascs. sionally legs as well as extensive gencralization, Good results had been obtained through the treat had been recognized. The disease was common _ ment trials by the usc of autogenous vaccine In evere in freisian than native breed and in generalized cases. Solitary large sessile warts and syoungs than adults and it occurred in some cascs — were removed surgically. For pedunculated, me-mixed with other infectious skin diseases as ring dium size and smiall solitary warts, cryosurgical worm or mange. treatment was highly beneficial.