Splenectomy in a camel under general anesthesia was successfully performed in the Vet. Clinic, Faculty of Agr. and Vet. Med. K. S. U. A comprehensive topographical anatomy of the spleen and its surface relations were mentioned. The laparotomy incision was made in the left flank from behind the last 12th rib at the end of the transverse process of the lst lumber, the incision took a downward and backward direction to the level of the 7th transverse lumber process with an angle of 45 degrees with the horizontal level. This approach gave enough scope for the operation field and space for ligating the splenic vessels.