This study was conducted to determine the effect of high dietary zinc (1000 ppm/kg ration) on serum total lipids, triacylglycerol, total cholesterol, phospholipids, high density lipoprotein cholesterol (HDLC), low density lipoprotein cholesterol (LDLC) and very low density lipoprotein cholesterol (VLDLC) of Hubberd broiler chickens for two and four weeks. The obtained data revealed that the high dietary zinc significantly (Ps 0.01) decreased both triacylglycerol and VLDLC throughout the experimental period. On the other hand, the total serum cholesterol and phospholipids were significantly decreased (P< -0.05) at 2nd week and highly significantly decreased (Ps 0.01) at 4 weeks. Moreover, the HDLC was significantly (ps 0.01) increased in treated group at 2nd and 4^th week. While the LDLC was significantly (ps0.01) decreased at 4th week. Serum total lipids showed no significant changes within the experimental period.