Fifty random samples of cream powders with vanilla and chocolate flavour were collected from supermarkets in different localities in Beni-Suef and Biza cities for determination of their bacteriological quality. The mean count of totla colongy count and coliforms in vanilla and chocolate cream powders'gm were 7.8 x 103 and 5.3 x 103 and 5.1 x 102 and 1.7 x 102 respectively. Str. faecalis. Str.intermediate and Str. faecium were detected at different percentages ranging from 12% to 44% of the examined samples.Aerobic spore formers and Anaerobes were detected in 68% & 32% and 56% & 20% of vanilla and chocolate cream powders samples respectively. Bacillus cereus, B. subtilis,  B. stearothermophillus and B. coagulance also clostridium perfringens, Cl. bifermentans, Cl. cadaveris and Cl.novyi could be isolated at varying percentages. The public health importance of existing organisms, their effect on the product as well as suggested control measures were discussed.