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372631

HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES

Article

Last updated: 23 Dec 2024

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-

Tags

Immunology / vaccine / diagnosis

Abstract

This study was planned to assess the use of highly immunogenic vaccine. Comparing between live and killed ND vaccine and between two types of killed vaccine were used: HB) live NDV vaccine, inactivated aluminum hydroxide gel formalized ND vaccine and inactivated oil ND vaccine. 210 one day old chicks having maternal immunity of mean HI titer 5.5 log were subjected to vaccination with the mentioned ND vaccines and the following results were obtained: The humoral immune response in chicks after vaccination with live vaccine alone resulted in higher mean HI titer (2.375 log? in 6th week post vaccination) than the use of killed vaccine alone. Inactivated oil emulsion ND vaccine alone induced higher level of humoral HI antibodies titer (1.75 log. in 6th week post Vaccination) than aluminum hydroxide gel formalized ND vaccine alone (1.5 log, in 6th week post vaccination). Also, the use of both live with oil vaccine produced higher humoral immune response (4.5 logy in 6th week post vaccination) than the use of live with aluminum hydroxide vaccine (3.5 log, in 6th week post vaccine. Study of the local immunity in vaccinated chicks for all groups revealed that these chicks have no local immunity. The challenge test applied 6 weeks post vaccination indicated that the protection percent was 50%, 62.5%, 87.5%,100% and 80% for the aluminum hydroxide vaccine, oil vaccine, aluminum hydroxide vaccine with live vaccine, oil vaccine with live vaccine and liver vaccine alone respectively.

DOI

10.21608/vmjg.1992.372631

Authors

First Name

MADKOUR

Last Name

S

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

First Name

MOHAMED

Last Name

T

MiddleName

-

Affiliation

Faculty of Veterinary Medicine, Cairo University.

Email

-

City

-

Orcid

-

First Name

NADIA

Last Name

HASSANS

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

First Name

KHOUDIR

Last Name

H

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

First Name

SALWA

Last Name

EL-ASSILE

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

First Name

ENSAF

Last Name

KHASHABAH

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

First Name

FEK- RIA

Last Name

EL-BORDINY

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

First Name

AFAF

Last Name

HADI

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

First Name

REDA

Last Name

I

MiddleName

-

Affiliation

Vet. Scrum & Vaccine Research Inst., Abbassia, Cairo.

Email

-

City

-

Orcid

-

Volume

40

Article Issue

3

Related Issue

49632

Issue Date

1992-07-01

Receive Date

2024-08-08

Publish Date

1992-07-01

Page Start

111

Page End

118

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 40_Issue 3_Pages 111-118.pdf

PDF . 2.6MB

Link

https://vmjg.journals.ekb.eg/article_372631.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=372631

Order

372,631

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

HUMORAL AND LOCAL IMMUNE RESPONSE TO DIFFERENT NEWCASTLE DISEASE VACCINES

Details

Type

Article

Created At

23 Dec 2024