In this study, we tried to increase the immunological response in cattle by feeding it with Zinc and or copper added to the ration at the same time of vaccination. Eight cattle were used in this study and divided into four groups two cattle (G1) were vaccinated with binary inactivated RVF vaccine only, two cattle (G2) were fed with zinc at the same time of vaccination and still fed with zinc for three successive days, two cattle (G3) were fed with copper at the same time of vaccination and still feed with copper for three successive days and two cattle (G4) were left as control of this study. The NI's of cattle to be protective from 2nd week (1.7 and 1.3) for zinc and copper respectively, while cattle vaccinated at the same time with RVF inactivated vaccine only was 1.4. The results of ELISA were in parallel to that obtained by S.N.T. From the previous results, it was concluded that the addition of zinc to the ration gave higher immune response in vaccinated animals compared with other groups.