Beta
370853

EFFECT OF THE PYRETHROID INSECTICIDE CYPERMETHRIN ON FERTILITY IN MALE RATS

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Miscellaneous
Pathology / oncology

Abstract

The effect of cypermethrin (ectomin) at two dos- age level on male reproductive organs were studied, the tested doses 1/40 and 1/30 LDs0, respectively were given for 65 successive days to male rats. Sex organ weight, semen picture, testosterone level were the criteria used to evaluate the productive efficiency of the treated male rats. Both doses decreased the weights of most genital organs, sperm cell concentration, percentage of live sperm, sperm motility and increased the percentage of total sperm, abnormalities. A decrease in the plasma testosterone level was observed in all treated groups. After 65 days on treatment and 30 days after last dose of drug administration as “compared to control group. Histopathological examiantion was carried out on testes and accessory glands (prostate and seminal vesicle) there was incomplete Spermatogenic process in the most of semineferous tubules, and activaiton of epithelial cell lining prostatic acini with polps formation protruded in the lumenae with cystic formation, while seminal vesicle showed cystic deilatation with polyps formation these changes were more potent in the large dose.    

DOI

10.21608/vmjg.1999.370853

Authors

First Name

MENHA

Last Name

ABD EL- KHALEK

MiddleName

-

Affiliation

Animal Health Research Institute Dokki-Giza, Toxicology unit

Email

-

City

-

Orcid

-

First Name

NARIMAN

Last Name

RAHMY

MiddleName

-

Affiliation

Animal Health Research Institute Dokki-Giza, Pathology unit.

Email

-

City

-

Orcid

-

First Name

H

Last Name

HALEEM

MiddleName

-

Affiliation

Animal Health Research Institute Dokki-Giza, Toxicology unit.

Email

-

City

-

Orcid

-

Volume

47

Article Issue

3

Related Issue

49549

Issue Date

1999-07-01

Receive Date

2024-07-30

Publish Date

1999-07-01

Page Start

295

Page End

305

Print ISSN

1110-1423

Online ISSN

2537-1045

Link

https://vmjg.journals.ekb.eg/article_370853.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=370853

Order

370,853

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

EFFECT OF THE PYRETHROID INSECTICIDE CYPERMETHRIN ON FERTILITY IN MALE RATS

Details

Type

Article

Created At

23 Dec 2024