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373658

Protective effects of date extract against toxic effects of lead acetate in rats

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Bacteriology and bacterial diseases
Epidemiology / public health

Abstract

Lead (Pb) is a common industrial and environmental pollutant, Prolonged exposure of a sublethal dose to this toxicant is associated with oxidative stress and considered to be a risk factor for kidney and liver in addition to many disorders. This study was carried out to investigate the most toxic effects of lead with a trial to diminish this toxicity by supplementation: of date extract, Both the enzymatic {superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPx) glutathione-S-transferase (GSH-T) and catalase (CAT)}, and non- enzymatic (glutathione, GSH) antioxidants has been studied among mature male albino rats which have been received lead acetate in drinking water for 3 months. It is widely accepted that even small quantities of Pb are harmful to rats which is implicated in a broad range of physiological conditions. The study proved that the use of date extract, through its antioxidant protective effect and immune potentiating properties, can reduce Pb-induced hepatic damage and toxicity.

DOI

10.21608/vmjg.2015.373658

Authors

First Name

Mahmoud

Last Name

Yasein

MiddleName

-

Affiliation

Graduate student, Faculty of Veterinary Medicine, Cairo University

Email

-

City

-

Orcid

-

First Name

El Jakee

Last Name

J

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Veterinary Medicine, Cairo University

Email

-

City

-

Orcid

-

First Name

Mervat

Last Name

M K

MiddleName

-

Affiliation

Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Cairo University

Email

-

City

-

Orcid

-

First Name

Hussein M

Last Name

Galal

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Veterinary Medicine, Cairo University

Email

-

City

-

Orcid

-

First Name

Tohamy

Last Name

A F

MiddleName

-

Affiliation

Department of Toxicology and Forensic Medicine, Faculty of Veterinary Medicine, Cairo University

Email

-

City

-

Orcid

-

First Name

Marouf

Last Name

Sherif

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Veterinary Medicine, Cairo University

Email

-

City

-

Orcid

-

Volume

61

Article Issue

3

Related Issue

49415

Issue Date

2015-07-01

Receive Date

2024-08-13

Publish Date

2015-07-01

Page Start

71

Page End

76

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 61_Issue 3_Pages 71-76.pdf

PDF . 3.2MB

Link

https://vmjg.journals.ekb.eg/article_373658.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=373658

Order

373,658

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

Protective effects of date extract against toxic effects of lead acetate in rats

Details

Type

Article

Created At

23 Dec 2024