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369364

SUCCESSFUL REVERSAL OF HYPERGLYCAEMIA IN DOGS WITHOUT IMMUNOSUPPRESSION

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Surgery, anesthesia, diagnostic imaging

Abstract

A natural macro-capsule consisted of a full-term pregnant bitch's amniotic membrane and pre- served porcine pancreatic islets of Langerhans was implanted intra-abdominally either in the omental pouch (group 1, n=6) or freely in the peritoneum (group 2, n=4) of alloxan induced dia- betic mongrel dogs. This macro-capsule constituted a biocompatible and permi-selective immune barrier containing purified porcine islets. It was able to reverse hyperglycemia in the diabetic dogs and did not lead to the hazards of artificial devices such as interstitial acute and chronic inflamma- tory reactions, development of granulation tissue and intestinal adhesions. Moreover, revascularizaTion of this natural membrane prolonged the survi- val and viability of islets.

DOI

10.21608/vmjg.2002.369364

Authors

First Name

M

Last Name

MAHGOUB

MiddleName

-

Affiliation

Islet Transplantation Research Center, Ain Shams University Hospital and Department of Surgery, Anaesthesiology and Radiology

Email

-

City

-

Orcid

-

First Name

A

Last Name

AMMAR

MiddleName

-

Affiliation

Islet Transplantation Research Center, Ain Shams University Hospital and Department of Surgery, Anaesthesiology and Radiology.

Email

-

City

-

Orcid

-

First Name

Y

Last Name

KHAMIS

MiddleName

-

Affiliation

Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

E

Last Name

SHETA

MiddleName

-

Affiliation

Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

H

Last Name

ABDEI AZIZ

MiddleName

-

Affiliation

Islet Transplantation Research Center, Ain Shams University Hospital and Department of Surgery, Anaesthesiology and Radiology

Email

-

City

-

Orcid

-

First Name

A

Last Name

EDRIS

MiddleName

-

Affiliation

Islet Transplantation Research Center, Ain Shams University Hospital and Department of Surgery, Anaesthesiology and Radiology

Email

-

City

-

Orcid

-

Volume

50

Article Issue

4

Related Issue

49349

Issue Date

2002-10-01

Receive Date

2024-07-26

Publish Date

2002-10-01

Page Start

905

Page End

909

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 50_Issue 4_Pages 905-909.pdf

PDF . 1.4MB

Link

https://vmjg.journals.ekb.eg/article_369364.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=369364

Order

369,364

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

SUCCESSFUL REVERSAL OF HYPERGLYCAEMIA IN DOGS WITHOUT IMMUNOSUPPRESSION

Details

Type

Article

Created At

23 Dec 2024