Fifty intestinal tract of domesticated turkeys were collected from private poultry markets in Zagazig city, Sharkia province for detection of protozoan parasites. Eleven out of fifty (22%) intestinal tract were infected with protozoan parasites. Seven of the examined samples (14%) were infected with three species of Eimeria: E. adenoeides 7/ 50 (14%): Emeleagrimitis 5/50 (10%) and Е.innocua 4/50 (8%). Three of the examined samples (6%) were infected with Cryptosporidi um meleagridis oocysts. Mixed infection with Tri- chomonads (Tetratrichomonas, gallinarum and Tritrichomonas eberthi) were detected in one of the examined samples (2%). Experimental infection of white albino rats with 10⁵ of C. meleagri- sqocysts revealed the presence of oocysts in dis faeces of infected rats 4 days post-infection. Histopathological examination of of different d organs of infected rats at 4 days post-infection showed endogenous developmental stages (trophozoites and schizonts) of C. meleagridis at brush border of tracheal epithelium. The characteristics morpho- logical features for the detected species were illustrated with photographs.