Out of 1060 feline patients admitted to Surgery clinic, Fac. Vet. Med., Cairo Uni. and two private clinics in Cairo, during the period from August 2001 to December 2003, 37 cats (3.5%) suffered obstipation and megacolon. Domestic shorthair cats represented 46% of the total affected cats with high incidence in Siamese breed. Out of the affected males, 19 (76%) were intact while the entire females were 8 (66.7%). The age of the affected cats ranged between 8-96 months. The clinical signs, clinical examination, probable causes and diagnostic radiographic imaging were recorded and discussed. Among surgical modalities used; transabdominal manipulation, colotomies and subtotal colectomy the latter one gave satisfactory results.