Common or red mites (Dermanyssus gallinae) cause a serious problem for poultry specially laying flocks. The manifestations of mites vary from a nuisance to death depending on the severity of infestation. Trials were conducted to control mites in laying poultry flock by using insecticides on birds and in the farm. 5 insecticides were used for spraying of the farm and poultry. Dimethoate (1%), malathion (5%), diazinon 60 (0.1%), butox 50 (0.1%) and metriphonate (0.15%). The first two were used in half strength for bird spraying with other insecticides, and the last two were used for dipping of infested birds. The results of this study indicated that the most effective insecticide as a building disinfestant was diazinon 60, which produced a complete reduction of mites at 12 hours post-treatment mean while butox 50 was effective in spraying and dipping of birds. It caused a reduction in mites infestation 100% and 95 % within 20 hours. respectively. It is clear that dipping of birds in insecticide solution is better than spray.