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386231

Organic Acids in Drinking Water Modulate the Humoral Immune Response and Performance of Broiler Chickens"

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Avian diseases / production
Immunology / vaccine / diagnosis
Management / housing / economics

Abstract

The high density and genetic homogeneity of poultry flock populations may make them susceptible to infectious diseases, and dysbiosis of their microbiomes and viromes may negatively impact their immune system and health. Generally, the poultry immune system is always under pressure from a high growth rate, pathogen challenge and high stocking density. Therefore, the need for natural products to modulate the immune system is necessary. Our study tries to investigate the ability of different organic acid supplements either in single or mixed forms by drinking water to enhance the broiler immune response, Feed conversion ratio (FCR) and broiler wellbeing. A total of 1800 Arbor Acres plus broiler chicks were divided into eight treated groups (200 chicks each) that received four different organic acids either in single or mixture and a ninth on-treated group was kept as a negative control group. All groups were vaccinated against avian influenza (H5N1, H5N8), (H9N2) and Newcastle disease (NDV). At age days 17 and 25, broilers were injected with sheep red blood cells (SRBCs). Sera samples were collected at 7, 25 and 35 days for hemagglutination inhibition assay (HI) to determine sheep red blood cells (SRBCs), NDV, H5N1, H5N8, and H9N2 antibody titres. Our results revealed that using organic acids either alone or in combination had a significant effect on enhancing and modulating the immune antibody titres against NDV, H5N1, H5N8, H9N2 and SRBCs. Additionally, all treated groups had lower FCR and broiler mortality, compared to the negative control group, as organic acids act as cosurfactant. In conclusion, our findings indicate the ability of organic acids alone or in mixtures to improve the broiler immune response against ND, H5, H9 and SRBCs, body weight and lower chick mortality.

DOI

10.21608/vmjg.2024.296320.1033

Keywords

Acidified drinking water, Antibody titre, Chick’s mortality, FCR, H5N1, H5N8, H9N2, ND, Immune Response, organic acid

Authors

First Name

Asmaa

Last Name

Ali

MiddleName

M.

Affiliation

Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.

Email

dr_fulla_2007@cu.edu.eg

City

Giza

Orcid

0000-0003-2140-2503

First Name

Abd Elrhman

Last Name

Gamal

MiddleName

M.

Affiliation

Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt

Email

abedelrhmangamal@gmail.com

City

-

Orcid

-

First Name

ٍRania

Last Name

El Naggar

MiddleName

F.

Affiliation

Department of Virology, Faculty of Veterinary Medicine, University of Sadat City, Sadat 32897, Egypt

Email

rania.elnagar@vet.usc.edu.eg

City

-

Orcid

-

First Name

Mohamed

Last Name

Rohaim

MiddleName

A.

Affiliation

Department of Virology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt 2 Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, UK

Email

mohammed_abdelmohsen@cu.edu.eg

City

-

Orcid

0000-0003-1798-7086

First Name

Mohamed

Last Name

Hamoud

MiddleName

M.

Affiliation

Department of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt

Email

mhmhamoud4@gmail.com

City

-

Orcid

-

First Name

Asmaa

Last Name

Morsi

MiddleName

S

Affiliation

Department of Physiology, Faculty of Veterinary Medicine, Cairo University

Email

-

City

-

Orcid

-

First Name

Shimaa

Last Name

Nasr

MiddleName

-

Affiliation

Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt

Email

shimaa_2003_3@hotmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Ali

MiddleName

-

Affiliation

Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt

Email

elsaid.samah@yahoo.com

City

-

Orcid

-

First Name

Samah

Last Name

Laban

MiddleName

E

Affiliation

Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt

Email

samahsaid8411@gmail.com

City

-

Orcid

-

Volume

70

Article Issue

1

Related Issue

49279

Issue Date

2024-07-01

Receive Date

2024-07-28

Publish Date

2024-07-01

Page Start

87

Page End

105

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 70_Issue 1_Pages 87-105.pdf

PDF . 994.1kB

Link

https://vmjg.journals.ekb.eg/article_386231.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=386231

Order

386,231

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

Organic Acids in Drinking Water Modulate the Humoral Immune Response and Performance of Broiler Chickens"

Details

Type

Article

Created At

23 Dec 2024