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368304

Preparation of Combined Equine Influenza and Tetanus Toxoid Vaccine from local stains

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Immunology / vaccine / diagnosis

Abstract

   Inactivated equine influenza from local isolate and tetanus toxoid (EITT) vaccine adjuvanted with saponin was prepared. It was inoculated into Guinea pigs as a preliminary evaluation for its potency, which exceeds the permissible protective level allowed to be used for vaccination of horses. The vaccine proved to be safe and potent for horses and Guinea pigs. The mean haemagglutination inhibition (HI) antibody titres (3 weeks post vaccination) were 704 and 200 and the mean toxin neutralizing (TN) antibodies (2 weeks after boostering) were 37.9 and 45 IU/ml respectively. The antibody titre in vaccinated hones was monitored up to 6 months post re- vaccination. The keeping quality of the prepared vaccine was studied for one year. It was found to be stable when stored at 4°C.

DOI

10.21608/vmjg.2011.368304

Authors

First Name

Soliman

Last Name

A

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

El-Meneisy

Last Name

A

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Nashwa

Last Name

Madkour

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

El-Helw

Last Name

A

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Eman

Last Name

Ebied

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Nehal

Last Name

Saleh

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Magda

Last Name

Kalad

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

Volume

59

Article Issue

3

Related Issue

49193

Issue Date

2011-07-01

Receive Date

2024-07-20

Publish Date

2011-07-01

Page Start

423

Page End

433

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 59_Issue 3_Pages 423-433.pdf

PDF . 1.8MB

Link

https://vmjg.journals.ekb.eg/article_368304.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=368304

Order

368,304

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

Preparation of Combined Equine Influenza and Tetanus Toxoid Vaccine from local stains

Details

Type

Article

Created At

23 Dec 2024