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368229

Improvement of Polyvalent Clostridial Vaccine

Article

Last updated: 03 Jan 2025

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Tags

Bacteriology and bacterial diseases

Abstract

    Rabbits, sheep and cattle were vaccinated with a prepared polyvalent clostridial vaccine adjuvenated with either alum or gel after addition of alpha toxoid of C. perferingens type A to polyvalent vaccine. The immune response of rabbits and sheep to the different components of the two vaccines was higher than these in cattle. The antitoxic values of rabbits, sheep and cattle for alpha and beta toxoid of C. perfringens type A and B, alpha toxoid of C. septicum and alpha toxoid of C. novyi type B in rabbits, sheep and cattle were higher in gel vaccine than in alum one, but the response to epsilon toxoid of C. perferingens type D was the same in both vaccines. Also the immune response of tetanus toxoid of C. tetani antigens and antigens of C. chauvoel bactrein and toxoid were higher in alum vaccine than in gel one. Finally both vaccines (alum and gel adjuvenated) gave satisfactory antibody titres which were higher than the minimum protective levels for all antigen components of both improved polyvalent clostridial vaccine.

DOI

10.21608/vmjg.2011.368229

Authors

First Name

Abdalla

Last Name

A

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

El-Meneisy

Last Name

A

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

El-Schiemy

Last Name

M

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Hussien

Last Name

S

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Ebtesam

Last Name

El-Sayed

MiddleName

-

Affiliation

Animal Fertility and Reproduction Research Institute, Harram, Giza, Egypt

Email

-

City

-

Orcid

-

First Name

Fathia

Last Name

Shafie

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbassia, Cairo, Egypt

Email

-

City

-

Orcid

-

Volume

59

Article Issue

3

Related Issue

49193

Issue Date

2011-07-01

Receive Date

2024-07-20

Publish Date

2011-07-01

Page Start

39

Page End

46

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 59_Issue 3_Pages 39-46.pdf

PDF . 1.2MB

Link

https://vmjg.journals.ekb.eg/article_368229.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=368229

Order

368,229

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

Improvement of Polyvalent Clostridial Vaccine

Details

Type

Article

Created At

23 Dec 2024