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367865

Studies on evaluation of inactivated lyophilized Equine Influenza vaccine in Egypt

Article

Last updated: 23 Dec 2024

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Subjects

-

Tags

Immunology / vaccine / diagnosis

Abstract

Two batches of egg adapted monovalent inactivated freeze dried equine influenza vaccine (EIV) were evaluated. There was no abnormal appearance of the freezed disc, prepared from locally isolated Strains. The efficacy was tested by lab animal (Guinea pigs) and target animal (horse). The vaccine proved to be safe and potent for both guinea pigs and horses. The mean haemagglutination inhibition (HI) antibodies of the vaccine reconstituted in DEAE-Dextran solution (as a solvent and adjuvant) were 120.4 and 153.7 in G. pigs, 179.2 and 230.4 in horses for the two batches of vaccine respectively. The keeping quality of the local prepared vaccine was studied, Shelf validity was stable at 4°C for one year, could be kept at -20°C for 3 years and 10 months at 40°C.

DOI

10.21608/vmjg.2011.367865

Authors

First Name

M

Last Name

Saad

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Nermin

Last Name

Shafik

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Amal

Last Name

Abdel Hadi

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Nassif

Last Name

A

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Safaa

Last Name

Warda

MiddleName

-

Affiliation

Vet. Serum and Vaccine Research Institute, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Sahar

Last Name

Saber

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Ali

Last Name

M

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo

Email

-

City

-

Orcid

-

First Name

Elham

Last Name

El-Ebiary

MiddleName

-

Affiliation

Central Laboratory for Evaluation of Vet. Biologics, Abbasia, Cairo

Email

-

City

-

Orcid

-

Volume

57

Article Issue

3

Related Issue

49189

Issue Date

2009-07-01

Receive Date

2024-07-17

Publish Date

2011-07-01

Page Start

485

Page End

495

Print ISSN

1110-1423

Online ISSN

2537-1045

Article File

VMJG_Volume 57_Issue 3_Pages 485-495.pdf

PDF . 2.8MB

Link

https://vmjg.journals.ekb.eg/article_367865.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=367865

Order

367,865

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

MainTitle

Studies on evaluation of inactivated lyophilized Equine Influenza vaccine in Egypt

Details

Type

Article

Created At

23 Dec 2024