Medicinal and surgical skin affections are common health problems in police guard and explosive dogs used for protection of organizations of high economic importance and tourism in Egypt. The present study was aimed to calculate the percentage of skin affections and to evaluate the degree of success for routine management of these problems. The study was performed on 156 working dogs where allergic conditions were represented by 7.7% with main complaint of severe pruritus. These conditions were constituted of flea allergic dermatitis (0.6%), contact allergic dermatitis (1.1%), food Allergy (4.1%), atopy (1.7%) and urticaria wheals after penicillin injection (0.24%). Surgical wounds shared with 14.3% and abscesses were represented by 0.35%. Insects (fleas) were represented by 0.6%, while acarides were represented by 24.4% which contained ticks (23.7%), sarcoptic mange (0.6%) with complaint of intense pruritus, and demodectic mange (0.12%). Fungal infection was represented by 0.35%. Ear affections included otitis externa (12.4%) and ear hematoma (2.9%). Pyoderma was represented by 20.3% which included surface pyoderma (18.3%), superficial pyoderma (1.72%) and deep pyoderma (0.24%). Tail arrada was represented by 1.5%. Scrotal affections were represented by 6.1%. Anal sacculitis was represented by 7%. Internal worms which induced bisymmetrical alopecia (5 cases of Dipylidium caninum, 6 cases of Toxocara canis in puppies, 3 cases of Toxascaris leoning in puppies) were represented by 1.7%. There were also reported 0.48% superficial swellings. The routine work was satisfactory in most cases except recurrent cases of pyoderma to which we recommended the use of alternative therapy.