The present study was carried out to investigate the effect of supplementation of turkey toms with basil, thyme, kemzyme either alone or in combination on the testicular performance. This study was carried on 36 male turkey toms three months old and the experiment extended for ten weeks. The toms were randomly divided into six groups (six birds each), the first group was fed the basal ration and considered as control group (C), the second group (B) fed on basal ration to which basil powder was added at a dose 3 g/ kg ration, (T) group fed on basal ration to which thyme powder was added at a dose 2 g/kg ration, (BT) group was fed basal ration to which basil and thyme powder were added with the same previous doses, group (K) was supplied with 0.5 g/kg ration kemzyme and the last group (BTK) was supplemented with a mix of basil, thyme and kemzyme with the same previous doses. Serum samples ere collected to measure some biochemical parameters, the testicular hormones (Estradiol 17 B and testosterone).At the same time testicular tissues were collected and prepared for morphological and molecular studies. Results of this study revealed that tom fed with either (B), (T) orb (BT) had significantly higher serum lipid level than both (C) and (k) groups. Supplementation with (k) significantly increases the estradiol 17 B and testosterone levels of turkey toms which accompanied with the lower level of serum lipid. Concerning the antioxidant total activities, in (B), (T), (BT) and (BTK) revealed a significant increase than its level in control group. Studies of intestinal morphology and integrity indicated that the group supplemented with (BTK) had a higher intestinal villous /crypts ratio plus increase in the goblet cell numbers. Moreover, the testicular tissue recorded an increase in both DNA concentration indicating increase cell size and accomplished with the increase of DNA/Protein which means increase of testicular cell mitosis. Thus the aim of the present study is to compare the effect of supplementing enzyme (Kemzyme), as commercial feed additives, to basil or thyme as natural feed additives and their combinations on some testicular performance.