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380826

Focus on Advancements in Amikacin Sulfate Delivery and Safety

Article

Last updated: 23 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Drug design and formulation

Abstract

Aminoglycosides  are  a  class  of  potent  antibiotics  widely  used  in the treatment of severe bacterial infections. However, their clinical efficacy  is  often  limited  by  issues  such  as  poor  bioavailability, systemic  toxicity,  and  the  emergence  of  antibiotic  resistance.  To overcome  these  challenges,  various  drug  delivery  systems  have been  developed  to  enhance  the  therapeutic  outcomes  of aminoglycosides.  This  review  article  provides  a  comprehensive overview  of  the  different  drug  delivery  systems  employed  for aminoglycosides,  with  a  specific  focus  on  amikacin.  The  review discusses  the  rationale  behind  the  use  of  drug  delivery  systems, the  various  types  of  delivery  systems  available,  their  advantages and limitations, and recent advancements in the field. The aim is to  provide  a  detailed  understanding  of  the  current  state-of-the-art drug delivery systems for aminoglycosides, particularly amikacin, and  their  potential  in  improving  the  clinical  outcomes  of aminoglycoside therapy. 

DOI

10.21608/rpbs.2024.308403.1312

Keywords

Aminoglycosides, Amikacin, drug delivery systems, Encapsulation, Nanoparticles, liposomes, hydrogels

Authors

First Name

Shadeed

Last Name

Gad

MiddleName

-

Affiliation

Faculty of Pharmacy - Suez Canal University

Email

shaded_abdelrahman@pharm.suez.edu.eg

City

Ismailia

Orcid

0000-0001-7714-2267

First Name

Mohamed

Last Name

Desoqi

MiddleName

-

Affiliation

Pharmacy Department, The Armed Forces Medical Complex, Qobry El Qoba, Ministry of Defense, Egypt

Email

mohamed.h.desoqi@gmail.com

City

-

Orcid

-

First Name

mohammed

Last Name

fawzy

MiddleName

-

Affiliation

Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.

Email

mohammed-fawzy@eru.edu.eg

City

-

Orcid

-

First Name

Mamdouh

Last Name

Ghourab

MiddleName

-

Affiliation

scu

Email

mghorab@hotmail.com

City

-

Orcid

-

First Name

Tamer

Last Name

Hassan

MiddleName

H.

Affiliation

Pharmaceutics & Industrial Pharmacy Department, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.

Email

tamer_hassan@pharm.suez.edu.eg

City

Ismailia

Orcid

0000-0002-9770-0382

First Name

Hossam

Last Name

elsawy

MiddleName

-

Affiliation

Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt

Email

hossam-elsawy@eru.edu.eg

City

-

Orcid

-

Volume

8

Article Issue

3

Related Issue

47569

Issue Date

2024-05-01

Receive Date

2024-07-30

Publish Date

2024-05-01

Page Start

132

Page End

143

Print ISSN

2536-9857

Online ISSN

2535-2091

Article File

RPBS_Volume 8_Issue 3_Pages 132-143.pdf

PDF . 1.1MB

Link

https://rpbs.journals.ekb.eg/article_380826.html

Detail API

https://rpbs.journals.ekb.eg/service?article_code=380826

Order

380,826

Type

Mini-reviews

Type Code

534

Publication Type

Journal

Publication Title

Records of Pharmaceutical and Biomedical Sciences

Publication Link

https://rpbs.journals.ekb.eg/

MainTitle

Focus on Advancements in Amikacin Sulfate Delivery and Safety

Details

Type

Article

Created At

23 Dec 2024